I was clicking to upgrade my weapons. The UI lagged. I clicked it again.. the UI lagged again.. I double-clicked.
Next thing I see, my quanta is negative several thousand.
The good: Quanta available tracked properly (it went negative, couldn't upgrade for a good while)
The bad: I had a massive tech advantage that I hadn't earned.
Screenshot from graph at end of game showing spike: http://imgur.com/KOop7bj