Probably this has been reported but when I first started up Ashes the opening screen locks and my mouse is unusable. There are a couple of solutions.
Starting up using "Launch DirectX 12 Version (Windows 10 Only)" instead of "Play Game..." solves the problem. When clicking on "Play Game..." I was able to get past the opening screen by doing a Control+Alt+Delete and going into Task Manager and attempting to stop gameoverlayui.exe. It restarts immediately but my mouse could now work and I could shut down the opening message screen which was causing the problem.
Get rid of the opening message screen would fix the issue period.
Almost requested a refund from Steam. I have a dim view of games that break immediately.
MSI GT72 6QD Dominator Laptop 17in screen + 2 x 24in Monitors.
32 GB RAM
1 TB SSD
Nividea GTX 970M
Windows 10 Home