If there was once weakness in that syste
Quoting T-revINoverdrive,
I'm not sure if my pc can run it. I have:
Settings 1920x1080p at high no MSAA Vsync enabled.
Windows 10
FX 8370 cpu bus 212 clocked at 4.65 ghz turbo
1 Sapphire Nitro+OC 8gb RX 480 at 1342 mhz
16gb G skill cas 7 clocked at 1867 mhz ram
Should I lower the graphics settings?
Should you lower the graphics? That is very much a personal choice depending on how you see the performance. If there was one weakness to your system I'd point to the CPU. I run Ashes on a 970 on Extreme, and your 480 is more powerful than my card so you should be more than fine on High. I am on an intel i7 4790k which is considered more powerful though, so it all depends on how much your CPU affects performance. Run the benchmark in dx11 and dx12 and see what you get. I would think your system would benefit very significantly from dx12. The benchmark is very taxing though so I would only take that as a very general guide, FPS is normally much higher in an actual game.
Edit: I will just add sometimes heavily overclocked CPUs, particularly AMDs, can result in less stable gameplay, as the game is able to use all the cores more effectively than most games so it will push them hard. If your gameplay is stable then you don't have to worry about it 
