reseach speed

If you go on https://www.galciv4.com/mods/manager and look for UP Bundle of Mods V4.1.05 or later, in there you'll find UP_MBC_TechPacingSlider that modifies how that bonus/malus is applied when using the tech slider. People who have tried it say they much prefer this way of doing it and the slower pacing. You can even change the values in there yourself if that's not slow enough for you.

I found pacing fille myself and changed to 2,50(-250%) every faction got 0 reseach point on start expect xenophobe and AI on higher difficultys

I need to find technology cost and double the costs cause pacing lower only research multiplayer  

You can do that but it'll be quite a manual job from the various techtree xmls.

Note that the mod I talked about also modifies how the pacing is applied; that alone may give you what you want.

you used <Value>-0.85</Value> there when very slow have <Value>-0.90</Value> normally, how it make it slower?

Because it applies it at a Faction level instead of colonies.

But really I'm just reporting what players have said throughout the years. Your own personal preference may diverge from their opinion.

and what is diffrence? it make it a lot of slower?

I've never extensively tested it myself, I'm just saying that user who tried it were satisfied with it. I do think it slows it down yes, even why it's set to -0.85 instead of 0.9 which would be even slower. Feel free to play with that value and have fun!

well it cut -85% total research not multiplayer on planet